I have been using Mcafee since 2017, and I am having this same issue recently.
The pop-up appears almost daily and it is not from my web browser as I have not enabled any extensions or have the web advisor on. I have spoken to the tech support regarding this, and the advice he gave me was to re-install Mcafee (Did not work).
The pop-up is harmless and is trying to be 'educational' for the incompetent users (perhaps?). Not having options to disable this is unacceptable. Mcafee is supposed to block irrelevant pop-ups, not creating one!