When the full Security Center is installed, it prevents links to MS Office 2003 from working. For example, if you use WE to fond a document and click on that document, the system freezes and the document won't open. A link in Outlook to an Office file exhibits the same behavior. The file open fine when opened directly by the Office application. The only way I was able to get McAfee to play with office was to completely uninstall it, including running MCPR and reinstall just the VirusScan and the Site Advisor. I have found no answers to this either on the MicroSoft or McAfee webiste.