Hello @Venkat_YM ,
McAfee is up to date. I can only guess that this started on the latest version because now we are up to 36GB in the folder [from Friday].
Unfortunately, I cannot get a screenshot of the issue.
When looking at C:\Quarantine it shows 36GB of .bup files
However, when in the VirusScan Console (as admin) and double click the Quarantine Manger Policy; it doesn't show a single file in the manager even though it is point at the C:\Quarantine folder.
For whatever reason, the console refuses to see the files and it seems they are locked by McAfee so even a local admin cannot delete them.