If it really is VirusScan 10 we're talking about then it isn't surprising as it's obsolete.
Please include the following information: What is your operating system, service pack and
are you up to date with Microsoft update?
What McAfee products do you have? If your taskbar icon is like this:

- right-click it and go to each application "About" and post the details.
If it is like this:

- double-click to open SecurityCenter and then click "View Details" or "About" at the lower right of the new window. Post the details from each module.
IE7 does not have any problems with McAfee and vice versa. IE
8 beta does, however.
Please reinstall IE7 to be securer.
Please post the information I've asked for, thanks.
Also when you say Security Center wont open, do you mean it wont open at all, or it opens blank?